Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope.

Gotch, F; McAdam, SN; Allsopp, CE; Gallimore, A; Elvin, J; Kieny, MP; Hill, AV; Mcmichael, AJ; Whittle, HC

Abstract:

A preliminary study of gag-specific, MHC-restricted CD8+ CTL has been performed in nine Gambian patients infected with HIV2. Such CTL were present in at least 55% of patients in fresh peripheral blood mononuclear cells without the requirement for in vitro restimulation. We have identified a nonamer peptide from HIV2 gag that is recognized by CD8+ HLA-B53 CTL using an amino acid sequence motif predicted from analysis of endogenous peptides eluted from HLA-B53 molecules. This peptide, from an H...

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APA Style

Gotch, F., McAdam, S. N., Allsopp, C. E., Gallimore, A., Elvin, J., Kieny, M. P., Hill, A. V., Mcmichael, A. J., & Whittle, H. C. (1993). Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope. Journal of Immunology (Baltimore, Md. : 1950), 151(6), 3361–3369.

MLA Style

Gotch, F., et al. “Cytotoxic T Cells in HIV2 Seropositive Gambians. Identification of a Virus-Specific MHC-Restricted Peptide Epitope.” Journal of Immunology (Baltimore, Md. : 1950), vol. 151, no. 6, Journal of immunology (Baltimore, Md. : 1950), 1993, pp. 3361–69.

Chicago Style

Gotch, F, SN McAdam, CE Allsopp, A Gallimore, J Elvin, MP Kieny, AV Hill, AJ Mcmichael, and HC Whittle. 1993. “Cytotoxic T Cells in HIV2 Seropositive Gambians. Identification of a Virus-Specific MHC-Restricted Peptide Epitope.” Journal of Immunology (Baltimore, Md. : 1950) 151 (6): 3361–69.
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