- Abstract:
-
A preliminary study of gag-specific, MHC-restricted CD8+ CTL has been performed in nine Gambian patients infected with HIV2. Such CTL were present in at least 55% of patients in fresh peripheral blood mononuclear cells without the requirement for in vitro restimulation. We have identified a nonamer peptide from HIV2 gag that is recognized by CD8+ HLA-B53 CTL using an amino acid sequence motif predicted from analysis of endogenous peptides eluted from HLA-B53 molecules. This peptide, from an H...
Expand abstract - Publication status:
- Published
- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 151
- Issue:
- 6
- Pages:
- 3361-3369
- Publication date:
- 1993-09-05
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:9bdd720c-4301-4347-883f-060570c5839d
- Source identifiers:
-
35663
- Local pid:
- pubs:35663
- Copyright date:
- 1993
Journal article
Cytotoxic T cells in HIV2 seropositive Gambians. Identification of a virus-specific MHC-restricted peptide epitope.
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