Journal article
Super-Resolved Traction Force Microscopy (STFM).
- Abstract:
- Measuring small forces is a major challenge in cell biology. Here we improve the spatial resolution and accuracy of force reconstruction of the well-established technique of traction force microscopy (TFM) using STED microscopy. The increased spatial resolution of STED-TFM (STFM) allows a greater than 5-fold higher sampling of the forces generated by the cell than conventional TFM, accessing the nano instead of the micron scale. This improvement is highlighted by computer simulations and an activating RBL cell model system.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 4.3MB, Terms of use)
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- Publisher copy:
- 10.1021/acs.nanolett.6b00273
Authors
- Publisher:
- American Chemical Society
- Journal:
- Nano Letters More from this journal
- Volume:
- 16
- Issue:
- 4
- Pages:
- 2633-2638
- Publication date:
- 2016-02-01
- Acceptance date:
- 2016-02-25
- DOI:
- ISSN:
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1530-6984, 1530-6992
- Pmid:
-
26923775
- Language:
-
English
- Keywords:
- Pubs id:
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pubs:609109
- UUID:
-
uuid:9bcafc29-32da-4fff-b27d-2b05d432d28a
- Local pid:
-
pubs:609109
- Source identifiers:
-
609109
- Deposit date:
-
2017-03-18
- ARK identifier:
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2016
- Notes:
- © 2016 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
- Licence:
- CC Attribution (CC BY)
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