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Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial.

Abstract:

BACKGROUND: Strontium ranelate is currently used for osteoporosis. The international, double-blind, randomised, placebo-controlled Strontium ranelate Efficacy in Knee OsteoarthrItis triAl evaluated its effect on radiological progression of knee osteoarthritis. METHODS: Patients with knee osteoarthritis (Kellgren and Lawrence grade 2 or 3, and joint space width (JSW) 2.5-5 mm) were randomly allocated to strontium ranelate 1 g/day (n=558), 2 g/day (n=566) or placebo (n=559). The primary endpoin...

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Publication status:
Published

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Journal:
Annals of the rheumatic diseases
Volume:
72
Issue:
2
Pages:
179-186
Publication date:
2013-02-05
DOI:
EISSN:
1468-2060
ISSN:
0003-4967
URN:
uuid:9bab5ff6-a0f5-4eb8-9675-6e59f68627fb
Source identifiers:
377408
Local pid:
pubs:377408

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