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Within-host evolution of Staphylococcus aureus during asymptomatic carriage

Abstract:

Staphylococcus aureus is a major cause of healthcare associated mortality, but like many important bacterial pathogens, it is a common constituent of the normal human body flora. Around a third of healthy adults are carriers. Recent evidence suggests that evolution of S. aureus during nasal carriage may be associated with progression to invasive disease. However, a more detailed understanding of within-host evolution under natural conditions is required to appreciate the evolutionary and mech...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pone.0061319

Authors


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Department:
Oxford, MSD, NDM, Human Genetics Wt Centre, BDI-NDM
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Department:
St Johns College
Miller, RR More by this author
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Department:
Oxford, MSD, Pathology Dunn School
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Wellcome Trust More from this funder
Department of Health More from this funder
Medical Research Council More from this funder
Biotechnology and Biological Sciences Research Council More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
8
Issue:
5
Pages:
e61319
Publication date:
2013-05-01
DOI:
EISSN:
1932-6203
Pubs id:
pubs:401163
URN:
uri:9b9ab315-4f6c-42d3-af6b-892cff35d110
UUID:
uuid:9b9ab315-4f6c-42d3-af6b-892cff35d110
Local pid:
pubs:401163

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