Primaquine radical cure in patients with Plasmodium falciparum malaria in areas co-endemic for P falciparum and Plasmodium vivax (PRIMA): a multicentre, open-label, superiority randomised controlled trial

Thriemer, K; Degaga, TS; Christian, M; Alam, MS; Rajasekhar, M; Ley, B; Hossain, MS; Kibria, MG; Tego, TT; Abate, DT; Weston, S; Mnjala, H; Rumaseb, A; Satyagraha, AW; Sadhewa, A; Panggalo, LV; Ekawati, LL; Lee, G; Anose, RT; Kiros, FG; Simpson, JA; Karahalios, A; Woyessa, A; Baird, JK; Sutanto, I; Hailu, A; Price, RN

Journal article

Primaquine radical cure in patients with Plasmodium falciparum malaria in areas co-endemic for P falciparum and Plasmodium vivax (PRIMA): a multicentre, open-label, superiority randomised controlled trial

Abstract:: Background
In areas co-endemic for Plasmodium vivax and Plasmodium falciparum there is an increased risk of P vivax parasitaemia following P falciparum malaria. Radical cure is currently only recommended for patients presenting with P vivax malaria. Expanding the indication for radical cure to patients presenting with P falciparum malaria could reduce their risk of subsequent P vivax parasitaemia.
Methods
We did a multicentre, open-label, superior... Expand abstract
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Thriemer, K., Degaga, T. S., Christian, M., Alam, M. S., Rajasekhar, M., Ley, B., Hossain, M. S., Kibria, M. G., Tego, T. T., Abate, D. T., Weston, S., Mnjala, H., Rumaseb, A., Satyagraha, A. W., Sadhewa, A., Panggalo, L. V., Ekawati, L. L., Lee, G., Anose, R. T., … Price, R. N. (2022). Primaquine radical cure in patients with Plasmodium falciparum malaria in areas co-endemic for P falciparum and Plasmodium vivax (PRIMA): a multicentre, open-label, superiority randomised controlled trial. Lancet, 402(10417), P2101–2110.

MLA Style

Thriemer, K., et al. “Primaquine Radical Cure in Patients with Plasmodium Falciparum Malaria in Areas Co-Endemic for P Falciparum and Plasmodium Vivax (PRIMA): a Multicentre, Open-Label, Superiority Randomised Controlled Trial.” Lancet, vol. 402, no. 10417, Elsevier, 2022, pp. P2101–2110.

Chicago Style

Thriemer, K, TS Degaga, M Christian, MS Alam, M Rajasekhar, B Ley, MS Hossain, et al. 2022. “Primaquine Radical Cure in Patients with Plasmodium Falciparum Malaria in Areas Co-Endemic for P Falciparum and Plasmodium Vivax (PRIMA): a Multicentre, Open-Label, Superiority Randomised Controlled Trial.” Lancet 402 (10417): P2101–2110.
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