Journal article
Repurposing of potent drug candidates for multiparasite targeting
- Abstract:
- Parasite-directed drug discovery efforts require sustained and substantial scientific resources. Many eukaryotic parasites share similarities in metabolic pathways and housekeeping genes, as evident from their underlying protein sequences. Their subsequent structural congruence within enzyme active sites can thus be leveraged for multiparasite targeting using similar or identical drug probes. This bodes well for delivering new anti-infectives.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
- Publisher:
- Cell Press
- Journal:
- Trends in Parasitology More from this journal
- Volume:
- 33
- Issue:
- 3
- Pages:
- 158-161
- Publication date:
- 2017-01-09
- Acceptance date:
- 2016-01-01
- DOI:
- EISSN:
-
1471-5007
- ISSN:
-
1471-4922
- Pubs id:
-
pubs:697690
- UUID:
-
uuid:9b71b01b-5ac0-40fc-98f3-421b07382b20
- Local pid:
-
pubs:697690
- Source identifiers:
-
697690
- Deposit date:
-
2017-05-30
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2017
- Notes:
- © 2017 Elsevier Ltd. All rights reserved.
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