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Role and regulation of MITF in melanocytes and melanoma

Abstract:

One key to understanding how cells integrate and how they respond to diverse stimuli in order to direct a transcriptional response is knowing how a transcription factor may be directed to an appropriate subset of its target genes. One mechanism with which this may be achieved is by modulation of the transcription factor’s post-translational modification status. The microphthalmia-associated transcription factor (MITF) is the master regulator of the melanocyte lineage, and it is al...

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Institution:
University of Oxford
Oxford college:
Queen's College, The
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
Role:
Author

Contributors

Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:9a6d568f-ab2c-4821-aecc-51adf5190118
Local pid:
ora:9645
Language:
English
Keywords:
Subjects:

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