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Journal article

T cell suppression in transplantation tolerance through linked recognition.

Abstract:

Allogeneic tissues transplanted to mice treated with CD4- and CD8-specific Abs are often accepted indefinitely due to the induction of immunologic tolerance. When transplantation tolerance was induced to grafts mismatched at multiple minor histocompatibility loci, Ag specificity was inferred because third party grafts, mismatched at the MHC, were rejected normally. However, some "third party" grafts were either accepted, or rejected more slowly. Tolerant mice possess CD4+ cells, which suppres...

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Publication status:
Published

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Authors


Davies, JD More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
156
Issue:
10
Pages:
3602-3607
Publication date:
1996-05-05
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:9a3a09bd-389c-4e2d-ba09-38a2cfed74b5
Source identifiers:
8521
Local pid:
pubs:8521

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