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The impact of inpatient bloodstream infections caused by antibiotic-resistant bacteria in low- and middle-income countries: A systematic review and meta-analysis

Abstract:

BACKGROUND: Bloodstream infections (BSIs) produced by antibiotic-resistant bacteria (ARB) cause a substantial disease burden worldwide. However, most estimates come from high-income settings and thus are not globally representative. This study quantifies the excess mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and economic costs associated with ARB BSIs, compared to antibiotic-sensitive bacteria (ASB), among adult inpatients in low- and middle-income countries...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1004199

Authors

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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-2144-7181
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Role:
Author
ORCID:
0000-0002-3787-6175
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Role:
Author
ORCID:
0000-0002-4425-1253
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Role:
Author
ORCID:
0000-0001-8605-3661
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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-8639-9846


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Funder identifier:
10.13039/501100020884
Grant:
73200098
More from this funder
Funder identifier:
10.13039/501100002850
Grant:
1211933


Publisher:
Public Library of Science
Journal:
PLoS Medicine More from this journal
Volume:
20
Issue:
6
Pages:
e1004199-e1004199
Publication date:
2023-06-22
DOI:
EISSN:
1549-1676
ISSN:
1549-1277


Language:
English
Keywords:
Pubs id:
1489524
Local pid:
pubs:1489524
Source identifiers:
W4381715943
Deposit date:
2026-05-11
ARK identifier:
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