Journal article icon

Journal article

CINC-1 is an acute-phase protein induced by focal brain injury causing leukocyte mobilization and liver injury.

Abstract:

Following injury or infection, the liver releases acute-phase proteins (APP). After a severe focal injury, this systemic response can be excessive and may lead to multiorgan dysfunction (MODS). CINC-1 is a neutrophil chemoattractant, and we have now established that it also functions as an early APP after injury to the brain or to peripheral tissues. After induction of a focal inflammatory lesion in the brain, there is rapid hepatic and serum CINC-1 induction, which is associated with increas...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1096/fj.02-0757fje

Authors


Campbell, SJ More by this author
Hughes, PM More by this author
Iredale, JP More by this author
Wilcockson, DC More by this author
Expand authors...
Journal:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Volume:
17
Issue:
9
Pages:
1168-1170
Publication date:
2003-06-05
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
URN:
uuid:99b0c7f1-3a44-40b8-a503-cbce032bd7d7
Source identifiers:
383078
Local pid:
pubs:383078

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP