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Nanoparticle delivery systems formed using electrically sprayed co-flowing excipients and active agent.

Abstract:

The high production rate generation of drug-loaded biodegradable nanoparticles is a crucial factor in achieving significant and rapid advances in nanomedicine. In this paper, we report a one-step, high yield, coaxial electrohydrodynamic spraying method for generating insulin-loaded polymeric nanoparticles. Poly(lactic-co-glycolic acid) copolymer (PLGA) was used as the model biodegradable polymer. The particle shape and size-distribution were studied using electron and atomic force microscopy ...

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Publisher copy:
10.1166/jbn.2011.1353

Authors


Bakhshi, R More by this author
Edirisinghe, M More by this author
Journal:
Journal of biomedical nanotechnology
Volume:
7
Issue:
6
Pages:
782-793
Publication date:
2011-12-05
DOI:
EISSN:
1550-7041
ISSN:
1550-7033
URN:
uuid:99793a15-125e-4b5d-889c-3ada3df342cb
Source identifiers:
327757
Local pid:
pubs:327757

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