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Journal article

Randomised controlled trial of urokinase versus placebo for non-draining malignant pleural effusion

Abstract:

Rationale

Patients with malignant pleural effusion (MPE) experience breathlessness, which is treated by drainage and pleurodesis. Incomplete drainage results in residual dyspnea and pleurodesis failure. Intrapleural fibrinolytics lyse septations within pleural fluid, improving drainage.

Objectives

To assess the effects of intrapleural urokinase on dyspnea and pleurodesis success in patients with non-draining malignant effusion.

Methods

Prospective ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1164/rccm.201704-0809oc

Authors


Mishra, EK More by this author
Davies, HE More by this author
Stanton, AE More by this author
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National Cancer Research Institute More from this funder
Publisher:
American Thoracic Society Publisher's website
Journal:
American Journal of Respiratory and Critical Care Medicine Journal website
Volume:
197
Issue:
4
Pages:
502-508
Publication date:
2018-02-15
Acceptance date:
2017-09-19
DOI:
EISSN:
1535-4970
ISSN:
1535-4970
Pubs id:
pubs:730014
URN:
uri:992c7e6f-d10f-41d3-b38c-43bc3f1e2dfe
UUID:
uuid:992c7e6f-d10f-41d3-b38c-43bc3f1e2dfe
Local pid:
pubs:730014
Language:
English
Keywords:

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