Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.

Journal article

Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.

Authors: Stoesser, N; Crook, D; Fung, R; Griffiths, D; Harding, R

• Publication status: Published
• Journal: Journal of clinical microbiology
• Volume: 49
• Issue: 11
• Pages: 3994-3996
• Publication date: 2011-11-01
• DOI: 10.1128/jcm.05349-11
• EISSN: 1098-660X
• ISSN: 0095-1137
• Language: English
• Keywords: Clostridium Infections; Genotype; Middle Aged; Adolescent; Aged; Clostridium difficile; Humans; Adult; Molecular Epidemiology; Infant; Great Britain; Ribotyping; Young Adult; DNA, Bacterial; Child, Preschool; Aged, 80 and over