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Individual fracture risk and the cost-effectiveness of bisphosphonates in patients using oral glucocorticoids.

Abstract:

OBJECTIVES: There are few data on the cost-effectiveness of bisphosphonates with oral glucocorticoids (GCs). An individual patient-based pharmaco-economic model was developed. METHODS: Data were obtained from a cohort of oral GC users aged 40+ (n = 190 000) in the UK General Practice Research Database. Individualized fracture and mortality risks were calculated specific for age, sex, daily and cumulative GC dose, indication and other clinical risk factors. UK costs of medication and direct co...

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Publication status:
Published

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Publisher copy:
10.1093/rheumatology/kel249

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Journal:
Rheumatology (Oxford, England)
Volume:
46
Issue:
3
Pages:
460-466
Publication date:
2007-03-05
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:98873c53-40e2-499c-8729-3e0bfcd5e8aa
Source identifiers:
126613
Local pid:
pubs:126613

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