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Biomarkers and surrogates of acute rejection in vascularized composite allograft transplantation

Abstract:
This chapter summarizes current progress in the development of non-invasive skin and serum biomarkers and surrogates for the recognition or prediction of acute rejection (AR) in the field of vascularized composite allograft (VCA) transplantation. In particular, the chapter highlights key developments in the following pre-clinical and clinical areas of VCA biomarker and surrogate research: cell phenotypes within peripheral blood and tissue, gene expression profiling, donor-derived cell-free DNA, microRNA profiling, proteomics, imaging, sentinel skin flaps, microbiome, and future immune phenotyping techniques.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1201/9780429260179

Authors

Contributors

Role:
Editor
Role:
Editor
Role:
Editor


Publisher:
CRC Press
Host title:
Reconstructive Transplantation and Regenerative Medicine: The Emerging Interface
Pages:
121-148
Chapter number:
7
Series:
Gene and Cell Therapy
Place of publication:
Boca Raton
Publication date:
2021-11-12
Edition:
1st
DOI:
EISBN:
9780429260179
ISBN-10:
0429522320
ISBN-13:
9780429522321


Language:
English
Keywords:
Subtype:
Chapter
Pubs id:
1210639
Local pid:
pubs:1210639
Deposit date:
2022-09-02
ARK identifier:

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