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Consequences of relying on statistical significance: some illustrations

Abstract:
Background Despite regular criticisms of null hypothesis significance testing (NHST), a focus on testing persists, sometimes in the belief to get published and sometimes encouraged by journal reviewers. This paper aims to demonstrate known key limitations of NHST using simple nontechnical illustrations. Design The first illustration is based on simulated data of 20,000 studies that compare two groups for an outcome event. The true effect size (difference in e... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/eci.12912

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Role:
Author
ORCID:
0000-0002-2772-2316
Publisher:
Wiley
Journal:
European Journal of Clinical Investigation More from this journal
Volume:
48
Issue:
5
Article number:
e12912
Publication date:
2018-02-13
Acceptance date:
2018-02-13
DOI:
EISSN:
1365-2362
ISSN:
0014-2972
Pmid:
29438579
Language:
English
Keywords:
Pubs id:
pubs:825017
UUID:
uuid:97bdf8a3-2144-4b68-a107-929620722732
Local pid:
pubs:825017
Source identifiers:
825017
Deposit date:
2018-02-19

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