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Asymmetric Synthesis of Piperidines and Octahydroindolizines

Abstract:
The conjugate addition of a homochiral lithium amide to a ξ-hydroxy-α,β-unsaturated ester, followed by a one-pot, ring-closure-N-debenzylation protocol has been used in the asymmetric syntheses of (S)-coniine and (R)-δ-coniceine (isolated as the corresponding hydrochloride salts) and the bicyclic core of stellettamide A. © Georg Thieme Verlag Stuttgart.
Publication status:
Published

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Publisher copy:
10.1055/s-0029-1219346

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
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Journal:
SYNLETT
Volume:
2010
Issue:
4
Pages:
567-570
Publication date:
2010-03-01
DOI:
EISSN:
1437-2096
ISSN:
0936-5214
Source identifiers:
49007
Language:
English
Keywords:
Pubs id:
pubs:49007
UUID:
uuid:9778ef2f-bda2-49ce-b2da-406dfd196ffe
Local pid:
pubs:49007
Deposit date:
2012-12-19

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