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Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies.

Abstract:

Background

Findings from previous studies showed that mepolizumab significantly reduces the rate of exacerbations in patients with severe eosinophilic asthma. To assess the relationship between baseline blood eosinophil counts and efficacy of mepolizumab we did a secondary analysis of data from two studies, stratifying patients by different baseline blood eosinophil thresholds.

Methods

We did a post-hoc analysis of data, which was completed on Sept 25, 2015, from t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2213-2600(16)30031-5

Authors


Publisher:
Elsevier
Journal:
Lancet Respiratory Medicine More from this journal
Publication date:
2016-05-01
DOI:
EISSN:
2213-2619
ISSN:
2213-2600


Language:
English
Pubs id:
pubs:623376
UUID:
uuid:9767397e-97be-4d77-ad84-988750ea0271
Local pid:
pubs:623376
Source identifiers:
623376
Deposit date:
2016-05-31
ARK identifier:

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