Journal article
AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?
- Abstract:
-
The cytoprotective effects of MK-801 and NBQX, selective N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonists, respectively, were compared both singularly and in combination in models of transient severe forebrain and transient focal cerebral ischemia. After 10 minutes of four-vessel occlusion ischemia, the sodium salt of NBQX (30 mg/kg IP) given at the time of reperfusion and, subsequently, 15 and 30 minutes later produced a dr...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Stroke; a journal of cerebral circulation
- Volume:
- 24
- Issue:
- 12 Suppl
- Pages:
- I148-I152
- Publication date:
- 1993-12-01
- EISSN:
-
1524-4628
- ISSN:
-
0039-2499
- Source identifiers:
-
80176
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:80176
- UUID:
-
uuid:9741943e-d589-4df6-96e5-3a2bc3be6030
- Local pid:
- pubs:80176
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1993
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