Journal article : Review
Long Term Metabolic Outcomes Following Pancreatectomy and Autologous Islet Transplantation: Systematic Review and Meta‐Analysis
- Abstract:
- This systematic review and meta‐analysis assessed long‐term outcomes following total pancreatectomy with islet autotransplantation (TPIAT). Seventeen studies including 1332 patients were analyzed. The pooled insulin independence rate was 34%, with higher rates for non‐chronic pancreatitis indications (68%) versus chronic pancreatitis (33%). TPIAT is effective in preserving endocrine function. Further studies are needed to validate outcomes across extended indications and to standardize reporting, incorporating metabolic markers and patient‐reported quality‐of‐life endpoints over long‐term follow‐up.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.7MB, Terms of use)
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- Publisher copy:
- 10.1002/jso.70193
Authors
- Publisher:
- Wiley
- Journal:
- Journal of Surgical Oncology More from this journal
- Publication date:
- 2026-01-08
- Acceptance date:
- 2026-01-03
- DOI:
- EISSN:
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1096-9098
- ISSN:
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0022-4790
- Language:
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English
- Keywords:
- Subtype:
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Review
- Pubs id:
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2374410
- UUID:
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uuid_971db682-cdc5-4dad-bcf7-c8ae5894b5b6
- Local pid:
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pubs:2374410
- Source identifiers:
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3646585
- Deposit date:
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2026-01-09
- ARK identifier:
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Terms of use
- Copyright date:
- 2026
- Licence:
- CC Attribution (CC BY)
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