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Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

Abstract:

BACKGROUND: Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for ischaemic stroke and its subtypes. METHODS: We meta-analysed data from 15 ischaemic stroke cohorts with a total of...

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Publication status:
Published

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Authors


Traylor, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Holliday, EG More by this author
Hopewell, JC More by this author
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Journal:
The Lancet. Neurology
Volume:
11
Issue:
11
Pages:
951-962
Publication date:
2012-11-05
DOI:
EISSN:
1474-4465
ISSN:
1474-4422
URN:
uuid:970585d7-10f2-4740-9612-f7fd982e24d5
Source identifiers:
354007
Local pid:
pubs:354007

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