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Journal article

The epidemiology and evolution of influenza A/H1N1 and A/H3N2 virus from 2010 to 2015, in Ho Chi Minh City, Vietnam

Abstract:
Influenza A viruses are highly infectious pathogens that constantly circulate in many animal hosts including humans, birds, pigs, horses and dogs. Infections with influenza viruses result in protective immunity mediated by antibodies against the viral surface glycoproteins hemagglutinin (HA) and neuraminidase (NA). However, human and some avian influenza viruses have continuously undergone antigenic evolution to evade pre-existing host immunity, a phenomenon known as antigenic drift (accumulation of point mutations in HA and NA antigens). Antigenic drift explains the occurrence of repeated seasonal influenza epidemics in humans. In order to determine the virus’ attack rate, cross-sectional seroprevalence studies are necessary.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/ve/vew036.007

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author


Publisher:
Oxford University Press
Journal:
Virus Evolution More from this journal
Volume:
3
Issue:
S1
Pages:
A8
Publication date:
2017-03-05
Acceptance date:
2016-01-01
DOI:
EISSN:
2057-1577
ISSN:
2057-1577


Language:
English
Pubs id:
pubs:726241
UUID:
uuid:96f89605-8b0d-42f2-9062-d226530a722e
Local pid:
pubs:726241
Source identifiers:
726241
Deposit date:
2017-09-13
ARK identifier:

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