Journal article
The epidemiology and evolution of influenza A/H1N1 and A/H3N2 virus from 2010 to 2015, in Ho Chi Minh City, Vietnam
- Abstract:
- Influenza A viruses are highly infectious pathogens that constantly circulate in many animal hosts including humans, birds, pigs, horses and dogs. Infections with influenza viruses result in protective immunity mediated by antibodies against the viral surface glycoproteins hemagglutinin (HA) and neuraminidase (NA). However, human and some avian influenza viruses have continuously undergone antigenic evolution to evade pre-existing host immunity, a phenomenon known as antigenic drift (accumulation of point mutations in HA and NA antigens). Antigenic drift explains the occurrence of repeated seasonal influenza epidemics in humans. In order to determine the virus’ attack rate, cross-sectional seroprevalence studies are necessary.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 33.1KB, Terms of use)
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- Publisher copy:
- 10.1093/ve/vew036.007
Authors
- Publisher:
- Oxford University Press
- Journal:
- Virus Evolution More from this journal
- Volume:
- 3
- Issue:
- S1
- Pages:
- A8
- Publication date:
- 2017-03-05
- Acceptance date:
- 2016-01-01
- DOI:
- EISSN:
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2057-1577
- ISSN:
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2057-1577
- Language:
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English
- Pubs id:
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pubs:726241
- UUID:
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uuid:96f89605-8b0d-42f2-9062-d226530a722e
- Local pid:
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pubs:726241
- Source identifiers:
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726241
- Deposit date:
-
2017-09-13
- ARK identifier:
Terms of use
- Copyright holder:
- Vy et al.
- Copyright date:
- 2017
- Notes:
- © 2017 The Authors. Published by Oxford University Press. This is an Open Access publication distributed under the terms of the Creative Commons Attribution Non-Commercial License. This article was presented at the 21st International BioInformatics Workshop on Virus Evolution and Molecular Epidemiology (Seoul, Republic of Korea: 14-19 August 2016).
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