Journal article
Cells within cells: rickettsiales and the obligate intracellular bacterial lifestyle
- Abstract:
- The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria that include many organisms of clinical and agricultural importance, including Anaplasma spp., Ehrlichia chaffeensis, Wolbachia, Rickettsia spp. and Orientia tsutsugamushi. This Review provides an overview of the current state of knowledge of the biology of these bacteria and their interactions with host cells, with a focus on pathogenic species or those that are otherwise important for human health. This includes a description of rickettsial genomics, bacterial cell biology, the intracellular lifestyles of Rickettsiales and the mechanisms by which they induce and evade the innate immune response.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Preview, Accepted manuscript, pdf, 308.7KB, Terms of use)
-
- Publisher copy:
- 10.1038/s41579-020-00507-2
Authors
- Publisher:
- Springer Nature
- Journal:
- Nature Reviews Microbiology More from this journal
- Volume:
- 19
- Issue:
- 2021
- Pages:
- 375–390
- Publication date:
- 2021-02-09
- Acceptance date:
- 2021-01-05
- DOI:
- EISSN:
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1740-1534
- ISSN:
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1740-1526
- Language:
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English
- Keywords:
- Pubs id:
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1161773
- Local pid:
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pubs:1161773
- Deposit date:
-
2021-02-16
- ARK identifier:
Terms of use
- Copyright holder:
- Springer Nature Limited
- Copyright date:
- 2021
- Rights statement:
- © Springer Nature Limited 2021
- Notes:
- This is the accepted manuscript version of the article. The final version is available from Springer Nature at: https://doi.org/10.1038/s41579-020-00507-2
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