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The immune response to Mycobacterium tuberculosis in HIV-infected and uninfected adults in Uganda: application of a whole blood cytokine assay in an epidemiological study.

Abstract:

SETTING: Out-patient clinic, Entebbe, Uganda. BACKGROUND: It has been proposed that 'type 1' cytokines are essential in protective immunity to Mycobacterium tuberculosis and that suppression of 'type 1' or a switch to a 'type 2' profile is deleterious. We employed a simple assay to examine whether the dependence of the immunological responses to mycobacterial antigens on a range of explanatory factors could be determined in a population where tuberculosis is endemic. OBJECTIVE: To determine t...

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Publication status:
Published

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Authors


Elliott, AM More by this author
Balyeku, MN More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NPEU
Kaleebu, P More by this author
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Journal:
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Volume:
3
Issue:
3
Pages:
239-247
Publication date:
1999-03-05
EISSN:
1815-7920
ISSN:
1027-3719
URN:
uuid:967083e6-80ed-456b-bedc-bcd5719e4203
Source identifiers:
484187
Local pid:
pubs:484187

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