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Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study

Abstract:
Background The recombinant vesicular stomatitis virus (rVSV) vaccine expressing the Zaire Ebola virus (ZEBOV) glycoprotein is efficacious in the weeks following single-dose injection, but duration of immunity is unknown. We aimed to assess antibody persistence at 1 and 2 years in volunteers who received single-dose rVSV-ZEBOV in three previous trials. Methods In this observational cohort study, we prospectively followed-up participants from the African and E... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S1473-3099(18)30165-8

Authors


Publisher:
Elsevier
Journal:
Lancet Infectious Diseases More from this journal
Volume:
18
Issue:
7
Pages:
738-748
Publication date:
2018-04-05
Acceptance date:
2018-02-04
DOI:
EISSN:
1474-4457
ISSN:
1473-3099


Pubs id:
pubs:891270
UUID:
uuid:9617ec77-41bd-40aa-9288-d3eeb9223b61
Local pid:
pubs:891270
Source identifiers:
891270
Deposit date:
2018-07-27
ARK identifier:

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