The future of restorative neurosciences in stroke: driving the translational research pipeline from basic science to rehabilitation of people after stroke.
BACKGROUND: Major advances during the past 50 years highlight the immense potential for restoration of function after neural injury, even in the damaged adult human brain. Yet, the translation of these advances into clinically useful treatments is painstakingly slow. OBJECTIVE: Here, we consider why the traditional model of a "translational research pipeline" that transforms basic science into novel clinical practice has failed to improve rehabilitation practice for people after stroke. RESUL...Expand abstract
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