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Synthesis of UDP-GlcNAc derivatives modified at OH-4 as potential chain-terminators of chitin biosynthesis

Abstract:
A series of UDP-GlcNAc derivatives and precursors that have been modified at the 4-position were synthesised from N-acetyl glucosamine as potential chain terminators of chitin biosynthesis. None of the UDP-derivatives or the precursors tested displayed any significant anti-fungal activity in cell adhesion or germination assays on the dermatophyte Trichophyton rubrum. © 2007 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Publisher copy:
10.1016/j.tetasy.2007.05.032

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
Journal:
TETRAHEDRON-ASYMMETRY More from this journal
Volume:
18
Issue:
11
Pages:
1299-1307
Publication date:
2007-06-22
DOI:
EISSN:
1362-511X
ISSN:
0957-4166
Language:
English
Pubs id:
pubs:40413
UUID:
uuid:95ab5b3a-7790-4f63-bc88-1100a2fcf32d
Local pid:
pubs:40413
Source identifiers:
40413
Deposit date:
2012-12-19

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