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Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

Abstract:

Impulse propagation in biological tissues is known to be modulated by structural heterogeneity. In cardiac muscle, improved understanding on how this heterogeneity influences electrical spread is key to advancing our interpretation of dispersion of repolarization. We propose fractional diffusion models as a novel mathematical description of structurally heterogeneous excitable media, as a means of representing the modulation of the total electric field by the ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1098/rsif.2014.0352

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Role:
Author
ORCID:
0000-0002-1634-3601
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Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Oxford college:
Green Templeton College
Role:
Author
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Role:
Author
ORCID:
0000-0001-8139-3480
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Oxford college:
St Cross College
Role:
Author
Publisher:
The Royal Society Publisher's website
Journal:
Journal of The Royal Society Interface Journal website
Volume:
11
Issue:
97
Pages:
20140352
Publication date:
2014-08-06
Acceptance date:
2014-05-21
DOI:
EISSN:
1742-5662
ISSN:
1742-5689
Pubs id:
pubs:469539
URN:
uri:959eac0b-cdeb-4e66-95e6-1bf2b4dc2c62
UUID:
uuid:959eac0b-cdeb-4e66-95e6-1bf2b4dc2c62
Local pid:
pubs:469539
Language:
English
Keywords:

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