Acute disseminated encephalomyelitis

Journal article

Acute disseminated encephalomyelitis (ADEM) is an acute widespread autoimmune demyelinating condition, which principally affects the white matter of the brain and spinal cord. It usually follows an infection or vaccination. The typical presentation is that of multifocal neurologic disturbances accompanied by change in mental status. CSF analysis reveals lymphocytic pleocytosis and elevated protein content, but may also yield normal results. MRI is regarded as the diagnostic imaging modality o...

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Authors: Politi, M; Papanagiotou, P; Grunwald, I; Roth, C; Reith, W

• Journal: Radiologe
• Volume: 48
• Issue: 6
• Pages: 553-559
• Publication date: 2008-06-01
• DOI: 10.1007/s00117-008-1693-y
• ISSN: 0033-832X
• Language: German
• Keywords: Magnetic resonance imaging (MRI); Acute disseminated encephalomyelitis (ADEM); White matter; Demyelination; Multiple sclerosis (MS)