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The effects of central catecholamine depletions on spatial learning in rats.

Abstract:

The role of forebrain catecholamine systems in spatial learning was assessed using a recently described place navigation task. Rats were required to learn the spatial location of a platform hidden 1 cm below the surface in order to escape from a large pool filled with opaque water. Circumscribed destruction of dopamine or noradrenaline neurones was achieved with bilateral stereotaxic injections of 6-hydroxydopamine. Rats with neostriatal dopamine depletions showed regulatory impairments, mild...

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Publication status:
Published

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Authors


Alpert, JE More by this author
Morris, RG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Journal:
Behavioural brain research
Volume:
9
Issue:
1
Pages:
83-104
Publication date:
1983-07-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:958629fd-d1f4-418a-9e37-830265114128
Source identifiers:
7798
Local pid:
pubs:7798

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