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Challenges in the reproducibility of clinical studies with resting state fMRI: An example in early Parkinson's disease.

Abstract:

Resting state fMRI (rfMRI) is gaining in popularity, being easy to acquire and with promising clinical applications. However, rfMRI studies, especially those involving clinical groups, still lack reproducibility, largely due to the different analysis settings. This is particularly important for the development of imaging biomarkers. The aim of this work was to evaluate the reproducibility of our recent study regarding the functional connectivity of the basal ganglia network in early Parkinson...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.neuroimage.2015.09.021

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
Szewczyk-Krolikowski, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
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Grant:
Monument Trust Discovery Award
National Institute for Health Research Oxford Biomedical Research Centre More from this funder
Publisher:
Elsevier Publisher's website
Journal:
NeuroImage Journal website
Volume:
124
Issue:
Pt A
Pages:
704-713
Publication date:
2016
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:95610f88-d23f-410e-8323-5fc2aa88b590
Source identifiers:
571605
Local pid:
pubs:571605

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