Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram

Journal article

The authors have retracted this article. After conducting replication experiments and reanalysing the original data, the authors discovered that the voltage imaging results, as presented in Figs.3a through 3f and Figs.4a andb, and discussed in the "Neurons gain cross-modal activation" section, are not reproducible. Additional voltage imaging work by the authors and their collaborators, for the conditions associated with Figs.3a through 3d, has not produced robust signals. Furthermore, errors in the pipeline originally used for data analysis could have led to the contamination of the F/F 0 data. A complete reanalysis by the authors of the voltage imaging data independently from the original pipeline did not replicate the original analysis. Although the authors have replicated the behavioural and connectomic data and consider that the general conclusions of the article are substantiated, the authors have no confidence in the voltage imaging data.

Authors: Okray, Z; Jacob, PF; Stern, C; Desmond, K; Otto, N

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Nature Research
• Journal: Nature
• Pages: 1-1
• Publication date: 2026-03-25
• DOI: 10.1038/s41586-026-10355-4
• EISSN: 1476-4687
• ISSN: 0028-0836
• Language: English
• Keywords: Memory formation; Mammalian brain; Neuroscientist; Engram