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Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis

Abstract:

OBJECTIVE To assess the effectiveness and safety of different preparations and doses of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip osteoarthritis pain and physical function to enable effective and safe use of these drugs at their lowest possible dose. DESIGN Systematic review and network meta-analysis of randomised trials. DATA SOURCES Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, regulatory agency webs...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmj.n2321
Publication website:
https://discovery.ucl.ac.uk/10136531/1/bmj.n2321.full.pdf

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Role:
Author
ORCID:
0000-0002-1786-6332
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Role:
Author
ORCID:
0000-0002-8574-832X
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Role:
Author
ORCID:
0000-0001-5902-8962
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Role:
Author
ORCID:
0000-0002-7863-5044
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Role:
Author
ORCID:
0000-0002-9587-7459


Publisher:
BMJ
Journal:
The BMJ More from this journal
Volume:
375
Pages:
n2321-n2321
Publication date:
2021-10-12
DOI:
ISSN:
1756-1833


Language:
English
Keywords:
Pubs id:
1280702
Local pid:
pubs:1280702
Source identifiers:
W3206683668
Deposit date:
2026-04-28
ARK identifier:
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