Journal article
Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT
- Abstract:
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BACKGROUND: Vasopressors are administered to critical care patients to avoid hypotension, which is associated with myocardial injury, kidney injury and death. However, they work by causing vasoconstriction, which may reduce blood flow and cause other adverse effects. A mean arterial pressure target typically guides administration. An individual patient data meta-analysis (Lamontagne F, Day AG, Meade MO, Cook DJ, Guyatt GH, Hylands M, et al. Pooled analysis of higher versus lower blood pressur...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.0MB, Terms of use)
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- Publisher copy:
- 10.3310/hta25140
Authors
+ Health Technology Assessment programme
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- Funder identifier:
- 10.13039/501100000664
- Grant:
- 15/80/39
- Publisher:
- NIHR Journals Library
- Journal:
- Health Technology Assessment More from this journal
- Volume:
- 25
- Issue:
- 14
- Pages:
- 1-90
- Publication date:
- 2021-02-01
- DOI:
- EISSN:
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2046-4924
- ISSN:
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1366-5278
- Language:
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English
- Keywords:
- Pubs id:
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1168731
- Local pid:
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pubs:1168731
- Source identifiers:
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W3133573859
- Deposit date:
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2026-02-14
- ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.
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- Copyright date:
- 2021
- Licence:
- CC Attribution (CC BY)
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