- Abstract:
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Fetal hemoglobin (HbF) and peripheral hemoglobin oxygen saturation (SpO2) both predict clinical severity in sickle cell disease (SCD), while reticulocytosis is associated with vasculopathy, but there are few data on mechanisms. HbF, SpO2 and routine clinical and laboratory measures were available in a Tanzanian cohort of 1175 SCD individuals aged≥5years and the association with SpO2 (as response variable transformed to a Poisson distribution) was assessed by negative binomial model with age a...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 299.0KB)
-
- Publisher copy:
- 10.1016/j.ebiom.2017.08.006
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- Publisher:
- Elsevier Publisher's website
- Journal:
- EBioMedicine Journal website
- Volume:
- 23
- Pages:
- 146-149
- Publication date:
- 2017-08-05
- Acceptance date:
- 2017-08-05
- DOI:
- EISSN:
-
2352-3964
- Pubs id:
-
pubs:726003
- URN:
-
uri:949432ca-f7f6-437e-b229-98ff507ccc5b
- UUID:
-
uuid:949432ca-f7f6-437e-b229-98ff507ccc5b
- Local pid:
- pubs:726003
- Language:
- English
- Keywords:
- Copyright holder:
- Newton et al
- Copyright date:
- 2017
- Notes:
- © 2017 Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Journal article
Fetal hemoglobin is associated with peripheral oxygen saturation in sickle cell disease in Tanzania.
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