Multisystem cytomegalovirus end-organ disease in a patient with advanced HIV

Journal article

Cytomegalovirus (CMV) infection is common in people living with HIV, but multisystem CMV end-organ disease (EOD) is rare following the introduction of effective antiretroviral therapy. We present the case of a patient with advanced HIV and multisystem manifestations of CMV EOD. Contributions: This case report highlights the potential morbidity and mortality associated with CMV disease in patients with advanced HIV. Clinicians should be vigilant in considering CMV EOD in patients with advanced HIV and visual, neurological and gastointestinal symptoms.

Authors: Spies, R; Joubert, P; Chetty, D; Dlamini, S; Moosa, MS

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: AOSIS Publishing
• Journal: Southern African Journal of Infectious Diseases
• Volume: 37
• Issue: 1
• Pages: 468-468
• Publication date: 2022-11-08
• DOI: 10.4102/sajid.v37i1.468
• EISSN: 2313-1810
• ISSN: 2312-0053
• Language: English
• Keywords: Viral load; Human cytomegalovirus; Cytomegalovirus; Disease; Organ system; Pathology; Immunology; Virus; Sida; Intensive care medicine; Cytomegalovirus infection; Cytomegalovirus infections; Viral disease; Herpesviridae; AIDS-Related Opportunistic Infections; Medicine; Human immunodeficiency virus (HIV); Multisystem disease; Pediatrics; Antiretroviral therapy