Journal article
Synthesis of the anti-trypanosomal agent (±)-hydroxyanthecotulide by Cr(ii)-catalysed allylation and Meyer-Schuster rearrangement.
- Abstract:
- The first synthesis of the bioactive sesquiterpene lactone hydroxyanthecotulide is achieved in 7 steps, involving a stereocontrolled Cr(ii)-catalysed reaction of 3-(bromomethyl)furan-2(5H)-one with enynal 9 and a mild Au(i)-catalysed Meyer-Schuster rearrangement.
- Publication status:
- Published
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Authors
- Journal:
- Chemical Communications More from this journal
- Volume:
- 48
- Issue:
- 51
- Pages:
- 6349-6350
- Publication date:
- 2012-05-01
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
- Language:
-
English
- Pubs id:
-
pubs:332004
- UUID:
-
uuid:939e07eb-819f-461c-b43a-a72f0fea4432
- Local pid:
-
pubs:332004
- Source identifiers:
-
332004
- Deposit date:
-
2012-12-19
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- Copyright date:
- 2012
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