A common model for the breathlessness experience across cardiorespiratory disease

Finnegan, S; Pattinson, K; Sundh, J; Sköld, M; Janson, C; Blomberg, A; Sandberg, J; Ekström, M

Journal article

A common model for the breathlessness experience across cardiorespiratory disease

Abstract:: Chronic breathlessness occurs across many different conditions, often independently of disease severity. Yet, despite being strongly linked to adverse outcomes, the consideration of chronic breathlessness as a stand-alone therapeutic target remains limited. Here we use data-driven techniques to identify and confirm the stability of underlying features (factors) driving breathlessness across different cardiorespiratory diseases.
Questionnaire data on 182 participants with main diagnoses of asthma (21.4%), COPD (24.7%), heart failure (19.2%), idiopathic pulmonary fibrosis (18.7%), other interstitial lung disease (2.7%), and “other diagnoses” (13.2%) were entered into an exploratory factor analysis (EFA). Participants were stratified based on their EFA factor scores. We then examined model stability using 6-month follow-up data and established the most compact set of measures describing the breathlessness experience.
In this dataset, we have identified four stable factors that underlie the experience of breathlessness. These factors were assigned the following descriptive labels: 1) body burden, 2) affect/mood, 3) breathing burden and 4) anger/frustration. Stratifying patients by their scores across the four factors revealed two groups corresponding to high and low burden. These two groups were not related to the primary disease diagnosis and remained stable after 6 months.
In this work, we identified and confirmed the stability of underlying features of breathlessness. Previous work in this domain has been largely limited to single-diagnosis patient groups without subsequent re-testing of model stability. This work provides further evidence supporting disease independent approaches to assess breathlessness.

Publication status:: Published

Peer review status:: Peer reviewed

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Finnegan, S., Pattinson, K., Sundh, J., Sköld, M., Janson, C., Blomberg, A., Sandberg, J., & Ekström, M. (2021). A common model for the breathlessness experience across cardiorespiratory disease. European Respiratory Journal Open Research, 7(2).

MLA Style

Finnegan, S., et al. “A Common Model for the Breathlessness Experience across Cardiorespiratory Disease.” European Respiratory Journal Open Research, vol. 7, no. 2, European Respiratory Society, 2021.

Chicago Style

Finnegan, S, K Pattinson, J Sundh, M Sköld, C Janson, A Blomberg, J Sandberg, and M Ekström. 2021. “A Common Model for the Breathlessness Experience across Cardiorespiratory Disease.” European Respiratory Journal Open Research 7 (2).
Share
Print