Quantification of Plasmodium ex vivo drug susceptibility by flow cytometry.
The emergence and spread of multidrug-resistant Plasmodium falciparum and Plasmodium vivax highlights the need for objective measures of ex vivo drug susceptibility. Flow cytometry (FC) has potential to provide a robust and rapid quantification of ex vivo parasite growth.Field isolates from Papua, Indonesia, underwent ex vivo drug susceptibility testing against chloroquine, amodiaquine, piperaquine, mefloquine, and artesunate. A single nucleic acid stain (i.e., hydroethidine (HE) for P. falci...Expand abstract
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- Malaria journal Journal website
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- ARTN 417
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- Wirjanata et al.
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Copyright © 2015 Wirjanata et al.
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