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The rhizoferrin biosynthetic gene in the fungal pathogen Rhizopus delemar is a novel member of the NIS gene family

Abstract:

Iron is essential for growth and in low iron environments such as serum many bacteria and fungi secrete ferric iron-chelating molecules called siderophores. All fungi produce hydroxamate siderophores with the exception of Mucorales fungi, which secrete rhizoferrin, a polycarboxylate siderophore. Here we investigated the biosynthesis of rhizoferrin by the opportunistic human pathogen, Rhizopus delemar. We searched the genome of R. delemar 99-880 for a homologue of the bacterial NRPS-independen...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/j.biocel.2017.06.005

Authors


Carroll, CS More by this author
Grieve, CL More by this author
Murugathasan, I More by this author
Bennet, AJ More by this author
Czekster, CM More by this author
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Natural Sciences and Engineering Research Council of Canada More from this funder
Simon Fraser University More from this funder
Publisher:
Elsevier Publisher's website
Journal:
International Journal of Biochemistry and Cell Biology Journal website
Volume:
89
Pages:
136-146
Publication date:
2017-06-10
Acceptance date:
2017-06-03
DOI:
EISSN:
1878-5875
ISSN:
1357-2725
Pubs id:
pubs:890077
URN:
uri:92cf4df4-6023-42d6-b311-7366083d8db2
UUID:
uuid:92cf4df4-6023-42d6-b311-7366083d8db2
Local pid:
pubs:890077

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