Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials.

Journal article

OBJECTIVE: To assess the effects of the neuraminidase inhibitors oseltamivir and zanamivir in treatment of children with seasonal influenza and prevention of transmission to children in households. DESIGN: Systematic review and meta-analysis of data from published and unpublished randomised controlled trials. DATA SOURCES: Medline and Embase to June 2009, trial registries, and manufacturers and authors of relevant studies. Review methods Eligible studies were randomised controlled trials of neuraminidase inhibitors in children aged

Authors: Shun-Shin, M; Thompson, M; Heneghan, C; Perera, R; Harnden, A

• Publication status: Published
• Journal: BMJ (Clinical research ed.)
• Volume: 339
• Issue: aug10 1
• Pages: b3172
• Publication date: 2009-01-01
• DOI: 10.1136/bmj.b3172
• EISSN: 1756-1833
• ISSN: 0959-8138
• Language: English
• Keywords: Child, Preschool; Oseltamivir; Humans; Anti-Bacterial Agents; Influenza, Human; Bias (Epidemiology); Randomized Controlled Trials as Topic; Risk Factors; Asthma; Zanamivir; Otitis Media; Child; Infant; Enzyme Inhibitors; Antiviral Agents; Neuraminidase