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Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome

Abstract:

Tuberculous meningitis (TBM) is the most devastating form of tuberculosis. Both intracerebral and peripheral blood immune responses may be relevant to pathogenesis, diagnosis, and outcome. In this study, the relationship between pretreatment host response, disease phenotype, and outcome in Vietnamese adults with TBM was examined. Before treatment, peripheral blood IFN-γ ELISPOT responses to the Mycobacterium tuberculosis Ags ESAT-6, CFP-10, and purified protein...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4049/jimmunol.176.3.2007

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
American Association of Immunologists
Journal:
Journal of Immunology More from this journal
Volume:
176
Issue:
3
Pages:
2007-2014
Publication date:
2006-02-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Pmid:
16424233
Language:
English
Keywords:
Pubs id:
pubs:33364
UUID:
uuid:9284653a-2e35-4b1a-914f-f994fc19cb10
Local pid:
pubs:33364
Source identifiers:
33364
Deposit date:
2017-07-19

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