Journal article

Prognosis of cryptogenic stroke with PFO at older ages and implications for trials: Results from the Oxford Vascular Study, systematic review, and meta-analysis

Abstract:: Importance:
Patent foramen ovale (PFO) closure may prevent recurrent stroke after cryptogenic transient ischemic attack (TIA) or stroke (TIA/stroke) in patients aged 60 years or younger. Patent foramen ovale is associated with cryptogenic stroke in the older population, but risk of recurrence is unknown. Data on prognosis of patients receiving medical treatment at older ages (≥60 years) are essential to justify trials of PFO closure.

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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Mazzucco, S., Li, L., & Rothwell, P. M. (2020). Prognosis of cryptogenic stroke with PFO at older ages and implications for trials: Results from the Oxford Vascular Study, systematic review, and meta-analysis. JAMA Neurology, 77(10), 1279–1287.

MLA Style

Mazzucco, S, et al. “Prognosis of Cryptogenic Stroke with PFO at Older Ages and Implications for Trials: Results from the Oxford Vascular Study, Systematic Review, and Meta-Analysis.” JAMA Neurology, vol. 77, no. 10, 2020, pp. 1279–87.

Chicago Style

Mazzucco, S, L Li, and PM Rothwell. 2020. “Prognosis of Cryptogenic Stroke with PFO at Older Ages and Implications for Trials: Results from the Oxford Vascular Study, Systematic Review, and Meta-Analysis.” JAMA Neurology 77 (10): 1279–87.
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Files:: Mazzucco_et_al_Prognosis_of_cryptogenic.pdf

(Preview, Version of record, pdf, 415.9KB, Terms of use)

Publisher copy:: 10.1001/jamaneurol.2020.1948

Authors

+ Mazzucco, S More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Clinical Neurosciences
Role:: Author

+ Li, L More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Clinical Neurosciences
Role:: Author
ORCID:: 0000-0002-3636-8355

+ Rothwell, PM More by this author

Institution:: University of Oxford
Division:: MSD
Department:: Clinical Neurosciences
Role:: Author

+ Wellcome Trust More from this funder

Grant:: 104040/Z/14/Z

Publisher:: American Medical Association
Journal:: JAMA Neurology More from this journal
Volume:: 77
Issue:: 10
Pages:: 1279-1287
Publication date:: 2020-07-06
Acceptance date:: 2020-04-10
DOI:: 10.1001/jamaneurol.2020.1948
EISSN:: 2168-6157
ISSN:: 2168-6149
Pmid:: 32628255

Language:: English
Keywords:: FFR
Pubs id:: 1118730
Local pid:: pubs:1118730
Deposit date:: 2021-02-03
ARK identifier:: ark:/29072/ora_925fe6d364e24d42aa7a98bc53bdf8fb

Terms of use

Copyright holder:: Mazzucco et al.
Copyright date:: 2020
Rights statement:: © 2020 Mazzucco S et al. JAMA Neurology. Open Access: This is an open access article distributed under the terms of the CC-BY License.

Licence:: CC Attribution (CC BY)

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