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The tethered aminohydroxylation (TA) reaction.

Abstract:
Since Sharpless' discovery of the asymmetric aminohydroxylation (AA) reaction, a major challenge for chemists has been to find ways of controlling the regio- and stereochemical outcome of this important reaction. Detailed herein is a review of our novel approach towards gaining reliable and predictable regio- and stereocontrol through the use of a tethered carbamate to promote an intramolecular AA reaction, along with a description of the mechanism proposed for this new methodology.
Publication status:
Published

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Publisher copy:
10.1039/b305189g

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Organic and biomolecular chemistry More from this journal
Volume:
1
Issue:
12
Pages:
2025-2028
Publication date:
2003-06-01
DOI:
EISSN:
1477-0539
ISSN:
1477-0520


Language:
English
Pubs id:
pubs:32445
UUID:
uuid:92574b1e-8c4f-428d-9696-5c5169210766
Local pid:
pubs:32445
Source identifiers:
32445
Deposit date:
2012-12-19

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