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Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels

Abstract:

The ClC family of chloride channels are found throughout the eukaryotes and homologues are found among the prokaryotes. There are nine ClC chloride channels found in mammals that are expressed either ubiquitously or in specific tissues. They have a role in a broad spectrum of cellular functions, ranging from the control of electrical excitability of neurons and the maintenance of the balance of charge required in the acidification of organelles, to the regulation of cell volume. The physio...

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Institution:
University of Oxford
Research group:
Laboratory of Molecular Biophysics
Oxford college:
New College
Department:
Mathematical,Physical & Life Sciences Division

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Role:
Supervisor
Publication date:
2001
Type of award:
MSc
Level of award:
Masters
URN:
uuid:91b00817-fd03-42de-b40d-d0addea11807
Local pid:
ora:2741

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