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Regulation of expression of the erythropoietin gene.

Abstract:

Erythropoietin, a hormone produced in the adult kidney, controls erythrocyte production. In response to ischemic or hypoxic hypoxia, the level of expression of the gene increases markedly. We have a limited understanding of the factors governing the tissue specificity of erythropoietin gene expression but considerable progress has been made toward understanding the mechanisms that increase erythropoietin gene expression in response to hypoxia. An increase in transcription occurs, mediated (at...

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Authors


Maxwell, P More by this author
Ratcliffe, P More by this author
Journal:
Current opinion in hematology
Volume:
5
Issue:
3
Pages:
166-170
Publication date:
1998-05-05
DOI:
EISSN:
1531-7048
ISSN:
1065-6251
URN:
uuid:9166f918-0c43-49c7-8797-069db60e9166
Source identifiers:
74074
Local pid:
pubs:74074

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