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Journal article

Rab regulation by GEFs and GAPs during membrane traffic

Abstract:

Rab GTPases and their regulatory proteins play a crucial role in vesicle-mediated membrane trafficking. During vesicle membrane tethering Rab GTPases are activated by GEFs (guanine nucleotide exchange factors) and then inactivated by GAPs (GTPase activating proteins). Recent evidence shows that in addition to activating and inactivating Rab GTPases, both Rab GEFs and GAPs directly contribute to membrane tethering events during vesicle traffic. Other studies have extended the range of processe...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ceb.2019.03.004

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
Trinity College
Role:
Author
ORCID:
0000-0001-7518-253X
Publisher:
Elsevier
Journal:
Current Opinion in Cell Biology More from this journal
Volume:
59
Pages:
34-39
Publication date:
2019-04-10
Acceptance date:
2019-03-06
DOI:
EISSN:
1879-0410
ISSN:
0955-0674
Pmid:
30981180
Language:
English
Keywords:
Pubs id:
pubs:992580
UUID:
uuid:91574e98-56e1-43a7-8d2f-d181c8cb0ace
Local pid:
pubs:992580
Source identifiers:
992580
Deposit date:
2019-06-11

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