As part of a high-throughput structural analysis of SARS-coronavirus (SARS-CoV) proteins, we have solved the structure of the non-structural protein 9 (nsp9). This protein, encoded by ORF1a, has no designated function but is most likely involved with viral RNA synthesis. The protein comprises a single beta-barrel with a fold previously unseen in single domain proteins. The fold superficially resembles an OB-fold with a C-terminal extension and is related to both of the two subdomains of the S...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
The nsp9 replicase protein of SARS-coronavirus, structure and functional insights.
If you are the owner of this record, you can report an update to it here: Report update to this record