Journal article
The effects of host contact network structure on pathogen diversity and strain structure.
- Abstract:
-
For many important pathogens, mechanisms promoting antigenic variation, such as mutation and recombination, facilitate immune evasion and promote strain diversity. However, mathematical models have shown that host immune responses to polymorphic antigens can structure pathogen populations into discrete strains with nonoverlapping antigenic repertoires, despite recombination. Until now, models of strain evolution incorporating host immunity have assumed a randomly mixed host population. Here, ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.0402000101
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 101
- Issue:
- 29
- Pages:
- 10839-10844
- Publication date:
- 2004-07-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
209729
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:209729
- UUID:
-
uuid:90c4d985-a6b0-4d91-b1d0-8e5d045b7fd7
- Local pid:
- pubs:209729
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2004
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