Journal article
Synthesis of modified proteins via functionalization of dehydroalanine
- Abstract:
-
Dehydroalanine has emerged in recent years as a non-proteinogenic residue with strong chemical utility in proteins for the study of biology. In this review we cover the several methods now available for its flexible and site-selective incorporation via a variety of complementary chemical and biological techniques and examine its reactivity, allowing both creation of modified protein side-chains through a variety of bond-forming methods (C-S, C-N, C-Se, C-C) and as an activity-based probe in i...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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- Files:
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(pdf, 1.4MB)
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- Publisher copy:
- 10.1016/j.cbpa.2018.05.022
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Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Current Opinion in Chemical Biology Journal website
- Volume:
- 46
- Pages:
- 71-81
- Publication date:
- 2018-06-15
- Acceptance date:
- 2018-05-29
- DOI:
- EISSN:
-
1879-0402
- ISSN:
-
1367-5931
- Pubs id:
-
pubs:859660
- URN:
-
uri:90893143-96c8-4f50-ad6b-b0086ca00737
- UUID:
-
uuid:90893143-96c8-4f50-ad6b-b0086ca00737
- Local pid:
- pubs:859660
- Paper number:
- C
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Davis et al
- Copyright date:
- 2018
- Notes:
- © 2018 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creative-commons.org/licenses/by-nc-nd/4.0/).
- License:
- CC BY
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